Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.73 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.73 |
| ▸ | TNKS | O95271 | 12/20 | 0.70 |
| ▸ | PARP1 | P09874 | 4/20 | 0.70 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | GABRP | O00591 | 2/20 | 0.69 |
| ▸ | GABRD | O14764 | 2/20 | 0.69 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.69 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.69 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.69 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.69 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.69 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454554 | 0.86 | CSNK2A2 (0.67) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| SCHEMBL28306223 | 0.85 | PLA2G2A (0.73) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| SCHEMBL28256218 | 0.85 | PLA2G2A (0.64) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| SCHEMBL22166376 | 0.84 | PLA2G2A (0.68) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| Flavone SCHEMBL22977569 | 0.83 | TNKS (0.81) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| SCHEMBL7593917 | 0.83 | TNKS (1.00) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| SCHEMBL13831363 | 0.82 | PLA2G2A (0.69) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| SCHEMBL23070093 | 0.82 | TNKS (0.93) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| Flavone SCHEMBL15676601 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4ATNKSPARP1TNKS2 | |
| Flavone SCHEMBL30542161 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4ATNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632194-B | The method that Benzofurantone compound is prepared as CO source of release using iron pentacarbonyl | 陕西师范大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-105175375-B | The method that the acetylenic ketone protected using acetoxyl group prepares Benzofurantone compound | 陕西师范大学 | 2017-07-11 | — | — | CN | disclosed |
| CN-106632194-A | Method for preparing benzopyrone compound through adopting pentacarbonyl iron as CO release source | 陕西师范大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-105175375-A | Method for preparing benzopyrone compounds through adopting acetoxy protected alkynyl ketone | UNIV SHAANXI NORMAL | 2015-12-23 | — | — | CN | disclosed |