Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.68 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TNKS | O95271 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | GABRP | O00591 | 2/20 | 0.62 |
| ▸ | GABRD | O14764 | 2/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454554 | 0.91 | CSNK2A2 (0.67) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL27488775 | 0.85 | PLA2G2A (0.68) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL15931417 | 0.85 | PLA2G2A (0.68) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL20074668 | 0.85 | PLA2G2A (0.62) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL28050773 | 0.84 | PLA2G2A (0.73) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL12386457 | 0.83 | CSNK2A2 (0.58) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL11638800 | 0.83 | PLA2G2A (0.64) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL21634007 | 0.81 | PLA2G2A (0.58) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| SCHEMBL11635046 | 0.81 | FFAR1 (0.70) | PLA2G2APLA2G4AHPGDMAPTTP53 | |
| 6-Methylflavone SCHEMBL4648879 | 0.80 | TP53 (1.00) | PLA2G2APLA2G4AHPGDMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696635-B2 | Versatile ligand for palladium-catalyzed meta-C—H functionalizations of aromatic substrates | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696635-B2 | Versatile ligand for palladium-catalyzed meta-C—H functionalizations of aromatic substrates | PAH, AHR, DDC | PLA2G2A 3344/4885PLA2G4A 3674/4885HPGD 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.