SCHEMBL28050814

SCHEMBL28050814

C=CC(=O)O[Si](CCCCCCCCCCCCCCCC)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
HPGD P15428 1/20 0.43
ZDHHC20 Q5W0Z9 2/20 0.41
ZDHHC2 Q9UIJ5 2/20 0.41
THRB P10828 6/20 0.38
THRA P10827 4/20 0.38
FAAH O00519 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
EPHX1 P07099 3/20 0.33
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29156655 0.93 TSHR (0.46) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL29053271 0.86 TSHR (0.40) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL27985544 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL27699554 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL27795147 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL27985884 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL27743782 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL28814535 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL27985547 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB
SCHEMBL27699553 0.82 TSHR (0.54) TSHRHPGDZDHHC20ZDHHC2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117070139-A Low-temperature rapid-curing polyurea coating and curing device thereof 浙江锦丰新材料科技有限公司 2023-11-17 CN claimed
CN-109135180-A A kind of nano-PVC composite material of good weatherability 合肥连森裕腾新材料科技开发有限公司 2019-01-04 CN claimed
CN-105176343-B Polyurea waterproof coating and preparation method thereof 深圳市登晟科技有限公司 2018-05-11 CN claimed
CN-107779065-A A kind of polyurea waterproof coating material and preparation method thereof 宁波高新区夏远科技有限公司 2018-03-09 CN claimed
CN-107641444-A A kind of polyurea waterproof coating material and preparation method thereof 宁波高新区夏远科技有限公司 2018-01-30 CN claimed
CN-105176343-A Polyurea waterproof coating and preparation method thereof NINGBO SHENTAI DRY POWDER BUILDING MATERIAL CO LTD 2015-12-23 CN claimed
CN-117070139-A Low-temperature rapid-curing polyurea coating and curing device thereof 浙江锦丰新材料科技有限公司 2023-11-17 CN disclosed
CN-105176343-B Polyurea waterproof coating and preparation method thereof 深圳市登晟科技有限公司 2018-05-11 CN disclosed
CN-107779065-A A kind of polyurea waterproof coating material and preparation method thereof 宁波高新区夏远科技有限公司 2018-03-09 CN disclosed
CN-107641444-A A kind of polyurea waterproof coating material and preparation method thereof 宁波高新区夏远科技有限公司 2018-01-30 CN disclosed
CN-105176343-A Polyurea waterproof coating and preparation method thereof NINGBO SHENTAI DRY POWDER BUILDING MATERIAL CO LTD 2015-12-23 CN disclosed