SCHEMBL28050893

SCHEMBL28050893

C#Cc1cc(OCC)ccc1OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.46
KDM4E B2RXH2 3/20 0.44
TSHR P16473 2/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
EPHX1 P07099 1/20 0.39
ALDH1A1 P00352 4/20 0.39
MAPT P10636 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
TP53 P04637 2/20 0.39
MAPK1 P28482 2/20 0.39
CYP3A4 P08684 1/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ESR2 Q92731 1/20 0.39
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15116999 0.85 KDM4E (0.47) NQO1KDM4ETSHRMEN1KMT2A
SCHEMBL28307516 0.82 ALDH1A1 (0.41) TSHRMEN1KMT2ANPC1ALDH1A1
SCHEMBL16061418 0.81 KDM4E (0.47) NQO1KDM4ETSHRMEN1KMT2A
SCHEMBL17040984 0.80 TSHR (0.47) TSHRMEN1KMT2ANPC1ALDH1A1
SCHEMBL27811880 0.80 MEN1 (0.54) NQO1KDM4ETSHRMEN1KMT2A
SCHEMBL2809824 0.80 CALM1 (0.41) KDM4ETSHRMEN1KMT2ANPC1
SCHEMBL2808093 0.80 MAPT (0.54) KDM4ETSHRMEN1KMT2ANPC1
SCHEMBL27794473 0.76 NQO1 (0.41) NQO1KDM4ETSHRMEN1KMT2A
SCHEMBL2890250 0.76 TDP1 (0.37) KDM4EMEN1KMT2ATDP1ALDH1A1
SCHEMBL29657372 0.76 NQO1 (0.59) NQO1KDM4ETSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103958512-B The two substituted alkynyl benzene compound of 3,5-and salt thereof TAIHO PHARMACEUTICAL CO.,LTD. (JP) 2016-01-20 CN disclosed