Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 8/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051165 | 1.00 | KDM4E (0.51) | KDM4ECACNA1BMMP1MMP2MMP9 | |
| SCHEMBL8164747 | 0.81 | MMP1 (0.49) | CACNA1BMMP1MMP2MMP9MMP12 | |
| Cinnamyl Anthranilate SCHEMBL826957 | 0.80 | ALDH1A1 (0.63) | KDM4ECACNA1BMMP1MMP2MMP9 | |
| Cinnamyl Anthranilate SCHEMBL826956 | 0.80 | ALDH1A1 (0.63) | KDM4ECACNA1BMMP1MMP2MMP9 | |
| Cinnamyl Anthranilate SCHEMBL14764170 | 0.80 | ALDH1A1 (0.63) | KDM4ECACNA1BMMP1MMP2MMP9 | |
| SCHEMBL8788521 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1KMT2A | |
| SCHEMBL27669917 | 0.77 | MMP1 (0.45) | KDM4ECACNA1BMMP1MMP2MMP9 | |
| Cinnamyl Anthranilate SCHEMBL9957169 | 0.76 | ALDH1A1 (0.58) | KDM4ECACNA1BMMP1MMP2MMP9 | |
| SCHEMBL5132345 | 0.75 | HSD17B2 (0.59) | KDM4ECACNA1BMAPTEGFRALDH1A1 | |
| SCHEMBL5132344 | 0.75 | HSD17B2 (0.59) | KDM4ECACNA1BMAPTEGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294471-A | Synthetic method of alpha-amido-gamma-nitro succinate derivative | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | disclosed |