SCHEMBL28051270

SCHEMBL28051270

O=[N+]([O-])c1c(Cl)c(F)c(Cl)c(F)c1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 7/20 0.41
GRIN2D O15399 4/20 0.37
GRIN3B O60391 4/20 0.37
GRIN1 Q05586 4/20 0.37
GRIN2A Q12879 4/20 0.37
GRIN2B Q13224 4/20 0.37
GRIN2C Q14957 4/20 0.37
GRIN3A Q8TCU5 4/20 0.37
TDP1 Q9NUW8 3/20 0.34
HPGD P15428 2/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
HIF1A Q16665 1/20 0.34
TXNRD1 Q16881 1/20 0.34
TXNRD3 Q86VQ6 1/20 0.34
TXNRD2 Q9NNW7 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646968 0.90 TSHR (0.43) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL27990736 0.90 TSHR (0.46) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL9774958 0.85 TSHR (0.43) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL11214675 0.84 TSHR (0.46) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL28525347 0.84 TSHR (0.46) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL8086687 0.82 TSHR (0.44) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL3476651 0.80 TSHR (0.65) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL10710731 0.80 TSHR (0.65) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL28854521 0.80 TSHR (0.43) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL29133102 0.80 TSHR (0.39) TSHRALDH1A1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105236611-B A kind of processing method of benzene class waste water 浙江奇彩环境科技股份有限公司 2018-02-02 CN disclosed
CN-105130744-B A kind of 2,4 difluoro 3,5 dichloronitrobenzene synthesis 1,3,5 trichlorine, 2,4,6 trifluoro-benzene 浙江林江化工股份有限公司 2017-03-29 CN disclosed
CN-105236611-A Processing method of benzene waste water ZHEJIANG QECOTE ENVIRONMENTAL TECHNOLOGY CO LTD 2016-01-13 CN disclosed