SCHEMBL8086687

SCHEMBL8086687

O=[N+]([O-])c1c(F)c(F)c(F)c(F)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 7/20 0.39
GRIN2D O15399 3/20 0.36
GRIN3B O60391 3/20 0.36
GRIN1 Q05586 3/20 0.36
GRIN2A Q12879 3/20 0.36
GRIN2B Q13224 3/20 0.36
GRIN2C Q14957 3/20 0.36
GRIN3A Q8TCU5 3/20 0.36
TDP1 Q9NUW8 4/20 0.33
HPGD P15428 2/20 0.33
VCP P55072 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
HIF1A Q16665 1/20 0.33
TXNRD1 Q16881 1/20 0.33
TXNRD3 Q86VQ6 1/20 0.33
TXNRD2 Q9NNW7 1/20 0.33
NPC1 O15118 2/20 0.32
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603550 0.93 TSHR (0.43) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL4646968 0.93 TSHR (0.43) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL4603509 0.88 TSHR (0.43) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL27990736 0.87 TSHR (0.46) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL28525347 0.87 TSHR (0.46) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL8111807 0.82 TSHR (0.39) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL30786720 0.82 GRIN2D (0.42) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL28854521 0.82 TSHR (0.43) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL4814058 0.82 TSHR (0.39) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL28051270 0.82 TSHR (0.52) TSHRALDH1A1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6048986-A DEHYDRATION OF DIFLUOROPYROMELLITIC ACID TO FORM DIFLUOROPYROMELLITIC DIANHYDRIDE NIPPON TELEGRAPH AND TELEPHONE CORP. (JP) 2000-04-11 US disclosed
US-5849934-A Method for preparing aromatic compounds NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1998-12-15 US disclosed
US-5750731-A POLYIMIDE ANHYDRIDE MONOMERS NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-05-12 US disclosed
EP-0480266-B1 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH & TELEPHONE (JP) 1996-06-26 EP disclosed
US-5449741-A Electronics with impact strength NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1995-09-12 US disclosed
US-5233018-A Heat resistance and low optical transmission loss in the near-infrared region; integrated circuits NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1993-08-03 US disclosed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP disclosed