SCHEMBL2805128

SCHEMBL2805128

CCCC(F)C(F)(F)C(F)=C(C(=O)O)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7860280 0.78
SCHEMBL1706476 0.75 CHRM1 (0.41) CHRM1AKR1A1CHRM3HTR2AHTR2C
Hydrochloric Acid SCHEMBL11748281 0.74 CHRM1 (0.39) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL11748269 0.74 HDAC7 (0.35) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1648854 0.73 CHRM1 (0.37) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6593161 0.73 MAPT (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1534090 0.71 LMNA (0.30)
SCHEMBL17491874 0.70 MAPT (0.47) MAPT
SCHEMBL223579 0.70
SCHEMBL27211767 0.70 CHRM1 (0.34) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100316806-A1 ANTI-FROST COATING AND THE APPLICATION METHOD THEREOF INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2010-12-16 US claimed
EP-2236573-A1 AN ANTI-FROST COATING AND THE APPLICATION METHOD THEREOF Institute of Chemistry, Chinese Academy of Science (CN) 2010-10-06 EP claimed
US-8372484-B2 Anti-frost coating and the application method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2013-02-12 US disclosed
US-20100316806-A1 ANTI-FROST COATING AND THE APPLICATION METHOD THEREOF INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2010-12-16 US disclosed
EP-2236573-A1 AN ANTI-FROST COATING AND THE APPLICATION METHOD THEREOF Institute of Chemistry, Chinese Academy of Science (CN) 2010-10-06 EP disclosed