⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805128 | 0.78 | CHRM1 (0.32) | — | |
| SCHEMBL16825642 | 0.72 | MAPT (0.32) | — | |
| SCHEMBL17451260 | 0.72 | — | — | |
| SCHEMBL6935460 | 0.70 | — | — | |
| SCHEMBL17491874 | 0.69 | MAPT (0.47) | — | |
| Succinic Acid SCHEMBL27808810 | 0.68 | ALOX5 (0.39) | — | |
| SCHEMBL725586 | 0.68 | — | — | |
| SCHEMBL29561692 | 0.68 | MAPT (0.39) | — | |
| SCHEMBL848623 | 0.68 | MAPT (0.59) | — | |
| SCHEMBL27786943 | 0.67 | ALOX15 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082142-A2 | COMPOSITIONS AND METHODS FOR DELIVERY OF GENETIC MATERIAL FOR ALTERING NEURONAL GROWTH, REGENERATION, AND SURVIVAL | Selective Genetics, Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999066959-A9 | COMPOSITIONS AND METHODS FOR DELIVERY OF GENETIC MATERIAL FOR ALTERING NEURONAL GROWTH, REGENERATION, AND SURVIVAL | SELECTIVE GENETICS INC (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999066959-A2 | COMPOSITIONS AND METHODS FOR DELIVERY OF GENETIC MATERIAL FOR ALTERING NEURONAL GROWTH, REGENERATION, AND SURVIVAL | SELECTIVE GENETICS, INC. (US) | 1999-12-29 | — | — | WO | disclosed |