Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13192152 | 0.83 | ATM (0.52) | ATML3MBTL1MAOBMRGPRX4SGMS2 | |
| SCHEMBL448079 | 0.82 | MAOB (0.57) | ATML3MBTL1MAOBSGMS2XDH | |
| SCHEMBL18959092 | 0.82 | L3MBTL1 (0.51) | ATML3MBTL1MAOBSGMS2MAOA | |
| SCHEMBL19427248 | 0.82 | L3MBTL1 (0.51) | ATML3MBTL1MAOBMRGPRX4SGMS2 | |
| SCHEMBL8807037 | 0.80 | MAOB (0.60) | L3MBTL1MAOBSMN1; SMN2GAAMAOA | |
| SCHEMBL2700393 | 0.80 | MAOB (0.56) | L3MBTL1MAOBSMN1; SMN2GAAMAOA | |
| SCHEMBL3319165 | 0.79 | MAOB (0.49) | MAOBMAOAXDHFNTAFNTB | |
| Hydrochloric Acid SCHEMBL4488053 | 0.79 | MAOB (0.55) | L3MBTL1MAOBSMN1; SMN2GAAMAOA | |
| SCHEMBL19421176 | 0.78 | L3MBTL1 (0.48) | ATML3MBTL1MAOBMRGPRX4SGMS2 | |
| SCHEMBL19431639 | 0.78 | L3MBTL1 (0.48) | ATML3MBTL1MAOBMRGPRX4SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674098-B | N- (3- cyano -4- alkoxyl phenyl) pyridine carboxamides and application thereof | 中国医科大学 | 2019-07-02 | — | — | CN | disclosed |
| CN-105294584-A | 1-substituted phenyl-1H-1,2,3-triazole compound as well as preparation method and application thereof | UNIV CHINA MEDICAL | 2016-02-03 | — | — | CN | disclosed |