Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874712 | 0.86 | SGMS2 (0.52) | MAOBSGMS2L3MBTL1MAPTMAPK1 | |
| SCHEMBL6831100 | 0.86 | MAOB (0.49) | MAOBSGMS2MAPK1XDHALDH1A1 | |
| SCHEMBL4452726 | 0.86 | NPC1 (0.52) | MAOBSGMS2L3MBTL1MAPTMAPK1 | |
| SCHEMBL15602827 | 0.86 | SGMS2 (0.52) | MAOBSGMS2L3MBTL1MAPTMAPK1 | |
| SCHEMBL30257271 | 0.86 | SGMS2 (0.52) | MAOBSGMS2L3MBTL1MAPTMAPK1 | |
| SCHEMBL25079152 | 0.86 | SGMS2 (0.52) | MAOBSGMS2L3MBTL1MAPTMAPK1 | |
| SCHEMBL8808187 | 0.86 | ABCB1 (0.53) | SGMS2XDHFNTAFNTBPGGT1B | |
| SCHEMBL2657882 | 0.84 | SGMS2 (0.51) | MAOBSGMS2L3MBTL1MAPTMAPK1 | |
| SCHEMBL3922233 | 0.84 | SGMS2 (0.51) | MAOBSGMS2L3MBTL1MAPTMAPK1 | |
| SCHEMBL1749528 | 0.84 | RXRA (0.62) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431983-B | A kind of 2- benzyloxies benzonitrile class compound and preparation method thereof | 信阳师范学院 | 2018-06-15 | — | — | CN | claimed |
| CN-106431983-A | 2-benzyloxybenzonitrile compound and preparation method thereof | 信阳师范学院 | 2017-02-22 | — | — | CN | claimed |
| EP-1483247-B1 | ARYL SUBSTITUTED PYRIMIDINES AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2009-06-24 | — | — | EP | claimed |
| US-7229993-B2 | Aryl substituted pyrimidines and the use thereof | EURO-CELTIQUE S.A. (LU) | 2007-06-12 | — | — | US | claimed |
| US-20050176700-A1 | 7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension,cardiovascular or renal diseases | ACTELION PHARMACEUTICALS LTD. (CH) | 2005-08-11 | — | — | US | claimed |
| CN-1646500-A | Aryl substituted pyrimidines and the use thereof | EURO CELTIQUE SA (LU) | 2005-07-27 | — | — | CN | claimed |
| EP-1483247-A2 | ARYL SUBSTITUTED PYRIMIDINES AND THE USE THEREOF | Euro-Celtique S.A. (LU) | 2004-12-08 | — | — | EP | claimed |
| US-20030236273-A1 | Aryl substituted pyrimidines and the use thereof | EURO-CELTIQUE S.A. | 2003-12-25 | — | — | US | claimed |
| WO-2003076414-A2 | ARYL SUBSTITUTED PYRIMIDINES AND THE USE THEREOF | EURO-CELTIQUE S.A. (US) | 2003-09-18 | — | — | WO | claimed |
| WO-2025224512-A1 | NOVEL COMPOUND AS 17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 (HSD17B13) INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 삼진제약주식회사 | 2025-10-30 | — | — | WO | disclosed |
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | Clear Creek Bio, Inc. (US) | 2025-01-23 | — | — | US | disclosed |
| CN-113861069-B | Preparation method of nitrile compound | 陕西国际商贸学院 | 2023-06-16 | — | — | CN | disclosed |
| CN-116180112-A | Method for electrochemical synthesis of aryl nitrile by using dialkyl aryl phosphate | 河南大学 | 2023-05-30 | — | — | CN | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0835254-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1998-04-15 | — | — | EP | disclosed |
| WO-1996038444-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1996-12-05 | — | — | WO | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176700-A1 | 7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension,cardiovascular or renal diseases | REN, AGTR1, ACE | MAOB 579/4885SGMS2 4391/4885L3MBTL1 4871/4885 |
| US-20030236273-A1 | Aryl substituted pyrimidines and the use thereof | CACNA1S, CACNA1C, NCS1 | MAOB 836/4885SGMS2 4660/4885L3MBTL1 223/4885 |
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | ACE, PREP, PEPD | MAOB 693/4885SGMS2 3006/4885L3MBTL1 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.