1,2-Dichlorobenzene

1,2-Dichlorobenzene

SCHEMBL28051530

CCCCO.Clc1ccccc1Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
LMNA P02545 5/20 0.48
TSHR P16473 2/20 0.48
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.40
DRD3 P35462 1/20 0.38
PCSK9 Q8NBP7 1/20 0.38
CFTR P13569 1/20 0.37
TLR8 Q9NR97 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL7821653 0.91 LMNA (0.56) ALDH1A1LMNATSHRHPGDSMN1; SMN2
1,2-Dichlorobenzene SCHEMBL4065607 0.87 TSHR (0.56) ALDH1A1LMNATSHRHPGDHTT
2-Chlorophenol SCHEMBL28496302 0.87 ALDH1A1 (0.60) ALDH1A1LMNATSHRHPGDSMN1; SMN2
Chlorobenzene SCHEMBL8020577 0.84 ALDH1A1 (0.50) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
Undecane SCHEMBL27492416 0.82 TSHR (0.56) ALDH1A1LMNATSHRHPGDSMN1; SMN2
Nonane SCHEMBL10388422 0.82 TSHR (0.56) ALDH1A1LMNATSHRHPGDSMN1; SMN2
Dodecane SCHEMBL28192322 0.82 TSHR (0.56) ALDH1A1LMNATSHRHPGDSMN1; SMN2
1,2-Dichlorobenzene SCHEMBL7513099 0.82 TSHR (0.56) ALDH1A1LMNATSHRHPGDSMN1; SMN2
Chlorobenzene SCHEMBL28264407 0.82 ALDH1A1 (0.48) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
1,2-Dichlorobenzene SCHEMBL9003449 0.82 TSHR (0.62) ALDH1A1LMNATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851896-B Pincer complex bridged porphyrin conjugated polymer, and synthesis method and application thereof 武汉大学 2022-04-01 CN claimed
CN-112851896-A Pincer complex bridged porphyrin conjugated polymer, and synthesis method and application thereof 武汉大学 2021-05-28 CN claimed
CN-112574394-A 1,3, 5-tri (4-formylphenyl) benzene-based conjugated microporous polymer and preparation method thereof 台州学院 2021-03-30 CN claimed
CN-112574407-A Conjugated microporous polymer based on 2,4, 6-tri (4-aldehyde phenyl) -1,3, 5-triazine and preparation method thereof 台州学院 2021-03-30 CN claimed
CN-110687182-A Preparation method of electrochemical immunosensor for detecting prostate specific antigen 云南大学 2020-01-14 CN claimed
CN-106967216-A A kind of covalent organic framework material of imines connection and preparation method and application 吉林大学 2017-07-21 CN claimed
CN-119869613-A Preparation of three-component covalent organic framework and application of three-component covalent organic framework in photocatalytic water decomposition 哈尔滨理工大学 2025-04-25 CN disclosed
CN-118325010-A Method for improving hydrogen storage performance of covalent organic framework compound and hydrogen storage application thereof 清华大学 2024-07-12 CN disclosed
CN-118325009-A Protonated covalent organic framework material and preparation method and application thereof 清华大学 2024-07-12 CN disclosed
CN-112574407-B 2,4,6-tri (4-aldehyde phenyl) -1,3,5-triazine-based conjugated microporous polymer and preparation method thereof 台州学院 2023-01-06 CN disclosed
CN-112851896-B Pincer complex bridged porphyrin conjugated polymer, and synthesis method and application thereof 武汉大学 2022-04-01 CN disclosed
CN-112646131-B Organic porous polymer and preparation method and application thereof 华南理工大学 2021-11-19 CN disclosed
CN-112851896-A Pincer complex bridged porphyrin conjugated polymer, and synthesis method and application thereof 武汉大学 2021-05-28 CN disclosed
CN-112646131-A Organic porous polymer and preparation method and application thereof 华南理工大学 2021-04-13 CN disclosed
CN-112574394-A 1,3, 5-tri (4-formylphenyl) benzene-based conjugated microporous polymer and preparation method thereof 台州学院 2021-03-30 CN disclosed
CN-112574407-A Conjugated microporous polymer based on 2,4, 6-tri (4-aldehyde phenyl) -1,3, 5-triazine and preparation method thereof 台州学院 2021-03-30 CN disclosed
CN-107540801-B Covalent organic framework and preparation method thereof 中国科学院上海有机化学研究所 2020-07-07 CN disclosed
CN-110687182-A Preparation method of electrochemical immunosensor for detecting prostate specific antigen 云南大学 2020-01-14 CN disclosed
CN-107540801-A A kind of covalently organic frame and preparation method thereof 中国科学院上海有机化学研究所 2018-01-05 CN disclosed
CN-105440058-A Synthesis method for benzothiazole unit-based covalent organic framework material UNIV LANZHOU 2016-03-30 CN disclosed