SCHEMBL28051576

SCHEMBL28051576

COc1c(Br)c(OC)c(OC)c(Br)c1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.55
CA4 P22748 7/20 0.55
CA1 P00915 7/20 0.55
CA6 P23280 5/20 0.55
PTPN1 P18031 2/20 0.52
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
CA9 Q16790 1/20 0.32
CA12 O43570 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ACHE P22303 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9549793 0.96 CA2 (0.52) CA2CA4CA1CA6PTPN1
SCHEMBL17910254 0.88 CA2 (0.60) CA2CA4CA1CA6PTPN1
SCHEMBL17910250 0.83 CA2 (0.55) CA2CA4CA1CA6PTPN1
SCHEMBL11103320 0.80 CA2 (0.52) CA2CA4CA1CA6PTPN1
SCHEMBL21883813 0.79 CA2 (0.40) CA2CA4CA1CA6PTPN1
SCHEMBL1275689 0.77 CA2 (0.44) CA2CA4CA1CA6PTPN1
SCHEMBL6754213 0.77 CA2 (0.39) CA2CA4CA1CA6PTPN1
SCHEMBL8250446 0.75 CA2 (0.42) CA2CA4CA1CA6PTPN1
SCHEMBL9814080 0.75 CA2 (0.42) CA2CA4CA1CA6PTPN1
SCHEMBL9070629 0.74 CA2 (0.42) CA2CA4CA1CA6PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105400509-A A method of generating fluorescence and phosphorescence through near ultraviolet and visible light absorption by organic compounds UNIV QINZHOU 2016-03-16 CN disclosed