Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250446 | 0.94 | CA2 (0.42) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL17772634 | 0.92 | CA2 (0.39) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL1275689 | 0.86 | CA2 (0.44) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL14098922 | 0.86 | CA2 (0.39) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL11268433 | 0.82 | CA2 (0.40) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL27279613 | 0.82 | ACHE (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27911882 | 0.80 | CA2 (0.50) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL1783863 | 0.80 | CA2 (0.39) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL9070629 | 0.79 | CA2 (0.42) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL2495732 | 0.78 | ACHE (0.36) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304777-B1 | PROCESS FOR THE PREPARATION OF CHROMAN DERIVATIVES OR OF D-ALPHA-TOCOPHEROL | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| US-4958035-A | Process for synthesizing chromanes | HOFFMANN-LA ROCHE INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4876369-A | Process for synthesizing chromanes | HOFFMANN-LA ROCHE INC. (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0304777-A2 | Process for the preparation of chroman derivatives or of d-alpha-tocopherol | F. HOFFMANN-LA ROCHE AG (CH) | 1989-03-01 | — | — | EP | disclosed |