SCHEMBL28051697

SCHEMBL28051697

CC(C)c1ccc(N)c(-c2cccc3c2C(C)(C)c2ccccc2-3)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.46
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
ALOX12 P18054 1/20 0.39
HTT P42858 1/20 0.39
HIF1A Q16665 1/20 0.39
LMNA P02545 2/20 0.37
FADS1 O60427 1/20 0.37
MAPT P10636 2/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HPGD P15428 1/20 0.36
GFER P55789 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
OPRK1 P41145 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NR1H3 Q13133 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21074052 0.79 ALDH1A1 (0.54) PDK2ALDH1A1GAALMNAMAPT
SCHEMBL29901014 0.79 ALDH1A1 (0.56) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL21142137 0.78 ALDH1A1 (0.52) PDK2ALDH1A1GAALMNAMAPT
Hydrochloric Acid SCHEMBL29900995 0.77 ALDH1A1 (0.54) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL17726793 0.76 ALDH1A1 (0.48) PDK2ALDH1A1GAALMNAMAPT
SCHEMBL29522609 0.76 ALDH1A1 (0.48) PDK2ALDH1A1GAALMNAMAPT
SCHEMBL28257639 0.75 KDM4E (0.48) PDK2ALDH1A1LMNAMAPTHPGD
SCHEMBL19847517 0.73 KDM4E (0.47) PDK2ALDH1A1LMNAMAPTHSD17B10
SCHEMBL7435713 0.73 ALDH1A1 (0.48) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL22182394 0.71 MAOA (0.46) PDK2ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105441066-A Organic electroluminescent material and application thereof VALIANT CO LTD 2016-03-30 CN disclosed