Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287718 | 0.85 | MAPT (0.41) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL17318505 | 0.73 | AKT1 (0.38) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL15058526 | 0.73 | AKT1 (0.38) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL31471657 | 0.73 | MAPT (0.43) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL11406085 | 0.73 | MAPT (0.43) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL7051343 | 0.71 | MAPT (0.39) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL3761806 | 0.71 | MAPT (0.42) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL6938598 | 0.71 | L3MBTL1 (0.39) | MAPTRECQLCYP3A4KMT2AALDH1A1 | |
| SCHEMBL10425119 | 0.71 | MAPT (0.45) | MAPTMAOBCYP1B1LMNARECQL | |
| SCHEMBL8617185 | 0.70 | ESR1 (0.33) | MAPTLMNARECQLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698492-B | 2-hydroxy chalcone amine compounds and application thereof | 四川大学 | 2020-07-03 | — | — | CN | claimed |
| CN-107698492-B | 2-hydroxy chalcone amine compounds and application thereof | 四川大学 | 2020-07-03 | — | — | CN | disclosed |
| CN-107698492-B | 2-hydroxy chalcone amine compounds and application thereof | 四川大学 | 2020-07-03 | — | — | CN | disclosed |
| CN-107698492-B | 2-hydroxy chalcone amine compounds and application thereof | 四川大学 | 2020-07-03 | — | — | CN | disclosed |
| CN-105439876-A | 2-hydroxy chalcone amine compound, preparation method and application thereof | UNIV SICHUAN | 2016-03-30 | — | — | CN | disclosed |
| CN-105439876-A | 2-hydroxy chalcone amine compound, preparation method and application thereof | UNIV SICHUAN | 2016-03-30 | — | — | CN | disclosed |