SCHEMBL5287718

SCHEMBL5287718

O=C(C=CC1C=CC=CC1(O)O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
RECQL P46063 2/20 0.41
PLIN1 O60240 2/20 0.41
LMNA P02545 2/20 0.41
PLIN5 Q00G26 2/20 0.41
ABHD5 Q8WTS1 2/20 0.41
MAOB P27338 2/20 0.41
BCHE P06276 1/20 0.41
TNFRSF1A P19438 1/20 0.41
ACHE P22303 1/20 0.41
CYP1B1 Q16678 1/20 0.41
ALDH1A1 P00352 5/20 0.38
RAB9A P51151 3/20 0.38
HPGD P15428 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
NFKB1 P19838 2/20 0.38
NFKB2 Q00653 2/20 0.38
RELA Q04206 2/20 0.38
NPC1 O15118 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28051708 0.85 MAPT (0.42) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL21807722 0.77 MAPT (0.39) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL21807724 0.77 MAPT (0.39) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL15058526 0.75 AKT1 (0.38) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL17318505 0.75 AKT1 (0.38) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL27821478 0.74 KMT2A (0.38) MAPTMAOBCYP1B1RAB9ANFKB1
SCHEMBL7051343 0.74 MAPT (0.39) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL10425119 0.73 MAPT (0.45) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL20300538 0.72 MAPT (0.40) MAPTRECQLPLIN1LMNAPLIN5
SCHEMBL28150514 0.72 NPC1 (0.43) MAPTRECQLLMNAMAOBBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12156832-B2 Method, and system for multi-layer cosmetic pads and use thereof ELC MANAGEMENT LLC (US) 2024-12-03 US disclosed
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-08-01 US disclosed
EP-4087441-A1 METHOD, AND SYSTEM FOR MULTI-LAYER COSMETIC PADS AND USE THEREOF ELC Management LLC (US) 2022-11-16 EP disclosed
WO-2021141926-A1 METHOD, AND SYSTEM FOR MULTI-LAYER COSMETIC PADS AND USE THEREOF ELC MANAGEMENT LLC (US) 2021-07-15 WO disclosed
US-20210205125-A1 Method, And System For Multi-Layer Cosmetic Pads and Use Thereof ELC MANAGEMENT LLC 2021-07-08 US disclosed
CN-102552083-B Composition containing Nitraria sibirica Pall extract and application thereof 强生消费者公司 2016-09-07 CN disclosed
CN-102552083-A Compositions comprising Lilium siberia extracts and uses thereof JOHNSON & JOHNSON CONSUMER 2012-07-11 CN disclosed
WO-2007016147-A2 TOPICAL SKIN PROTECTANT AND ANTI-PRURITIC COMPOSITIONS STIEFEL LABORATORIES, INC. (US) 2007-02-08 WO disclosed
US-6488947-B1 AND COSMETICALLY ACCEPTABLE CARRIER FOR BONDING AGENT THE PROCTER & GAMBLE COMPANY 2002-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS TYR, DOT1L, CUTA MAPT 1712/4885RECQL 1541/4885PLIN1 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.