SCHEMBL28051901

SCHEMBL28051901

O=[N+]([O-])C(CCO)Cc1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.43
SLC6A2 P23975 1/20 0.43
SLC7A5 Q01650 1/20 0.40
CA2 P00918 1/20 0.39
ESR1 P03372 4/20 0.38
ESR2 Q92731 4/20 0.38
TSHR P16473 1/20 0.37
CNR1 P21554 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28327168 0.86 SLC7A5 (0.42) TAAR1SLC6A2SLC7A5CA2ESR1
SCHEMBL7605614 0.80 ESR1 (0.47) TAAR1SLC6A2ESR1ESR2CNR1
SCHEMBL7094145 0.80 ESR1 (0.47) TAAR1SLC6A2ESR1ESR2CNR1
SCHEMBL27686381 0.80 MGLL (0.36) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL10455739 0.76 SLC7A5 (0.46) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL28051902 0.73 HSPA5 (0.38) TAAR1SLC6A2CA2TSHR
SCHEMBL27439459 0.71 TRPV1 (0.40) TAAR1SLC6A2ESR1ESR2CNR1
SCHEMBL30871914 0.70 SLC7A5 (0.53) TAAR1SLC6A2SLC7A5CA2ESR1
SCHEMBL28484973 0.70 TAAR1 (0.52) TAAR1SLC6A2SLC7A5CA2ESR1
SCHEMBL5981148 0.69 CPA1 (0.50) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330984-A TPV composition and automobile hand brake grip coating material ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2016-02-17 CN disclosed