SCHEMBL28051902

SCHEMBL28051902

O=[N+]([O-])C(CCO)Cc1ccccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.38
AKR1B1 P15121 1/20 0.38
MGLL Q99685 1/20 0.36
TSHR P16473 2/20 0.35
CYP2D6 P10635 2/20 0.35
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GSR P00390 1/20 0.35
CA12 O43570 2/20 0.35
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
IDO1 P14902 1/20 0.33
CYP3A4 P08684 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ITGA4 P13612 1/20 0.33
ITGB7 P26010 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL726420 0.87 HSPA5 (0.38) HSPA5AKR1B1MGLLTSHRCYP2D6
SCHEMBL11239755 0.81 MGLL (0.41) HSPA5AKR1B1MGLLTSHRCYP2D6
SCHEMBL28899674 0.81 MGLL (0.41) HSPA5AKR1B1MGLLTSHRCYP2D6
SCHEMBL10455741 0.78 HSPA5 (0.45) HSPA5AKR1B1MGLLTSHRCYP2D6
SCHEMBL27686233 0.77 TSHR (0.40) AKR1B1MGLLTSHR
SCHEMBL28051901 0.73 TAAR1 (0.43) TSHRCA2TAAR1SLC6A2
SCHEMBL29116349 0.72 HSPA5 (0.46) HSPA5AKR1B1TSHRCYP2D6HIF1A
SCHEMBL28472388 0.71 ITGA4 (0.40) HSPA5AKR1B1TSHRCYP2D6HIF1A
SCHEMBL10958798 0.70 HSPA5 (0.45) HSPA5AKR1B1TSHRCYP2D6HIF1A
SCHEMBL29729482 0.69 MGLL (0.44) HSPA5AKR1B1MGLLTSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330984-A TPV composition and automobile hand brake grip coating material ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2016-02-17 CN disclosed