Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 14/20 | 0.45 |
| ▸ | LPL | P06858 | 13/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562597 | 0.88 | ROCK1 (0.52) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL31643226 | 0.88 | ROCK1 (0.52) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL793337 | 0.86 | LIPG (0.57) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL18643675 | 0.83 | ROCK1 (0.56) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL17430653 | 0.81 | ROCK1 (0.52) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL3321140 | 0.81 | ROCK1 (0.55) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL27143661 | 0.80 | ROCK1 (0.55) | ROCK1LIPGLPLF11 | |
| SCHEMBL17419224 | 0.79 | ROCK1 (0.50) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL20665867 | 0.79 | ROCK1 (0.50) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL22664432 | 0.79 | ROCK1 (0.50) | ROCK1LIPGLPLCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102917590-B | Tricyclic compound and the PBK inhibitor containing described compound | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | disclosed |