Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775902 | 0.92 | CYP1A2 (0.60) | GSTP1MAOBALOX5TOP1LMNA | |
| SCHEMBL7685716 | 0.91 | MAOB (0.56) | GSTP1MAOBALOX5TOP1LMNA | |
| SCHEMBL26835446 | 0.83 | MAOB (0.52) | GSTP1MAOBALOX5TOP1MAOA | |
| SCHEMBL31069846 | 0.81 | LMNA (0.67) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL281986 | 0.81 | LMNA (0.67) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL3823883 | 0.81 | MAOB (0.62) | GSTP1MAOBALOX5TOP1LMNA | |
| SCHEMBL8612967 | 0.80 | GSTP1 (0.55) | GSTP1MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL8616187 | 0.80 | GSTP1 (0.55) | GSTP1MAOBALOX5TOP1LMNA | |
| SCHEMBL29978578 | 0.79 | GSTP1 (0.71) | GSTP1MAOBALOX5LMNACYP1A2 | |
| SCHEMBL8613858 | 0.79 | GSTP1 (0.54) | GSTP1MAOBALOX5LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452244-A | Benzothiophene derivatives as estrogen receptor inhibitors | GLAXOSMITHKLINE IP DEV LTD | 2016-03-30 | — | — | CN | disclosed |