Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 9/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281986 | 1.00 | LMNA (0.67) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL2900304 | 0.88 | LMNA (0.59) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL3823883 | 0.85 | MAOB (0.62) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8599201 | 0.83 | LMNA (0.68) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL31533149 | 0.83 | MAOB (0.60) | LMNAMAOBMAOARAB9ANR4A2 | |
| SCHEMBL30628889 | 0.82 | MAOB (0.59) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL615020 | 0.82 | MAOB (0.59) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL28052026 | 0.81 | GSTP1 (0.64) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL31748829 | 0.81 | MAOB (0.54) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL7775902 | 0.81 | CYP1A2 (0.60) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515682-A | Dolichosin A preparation method and intermediate thereof | 成都科岭源医药技术有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118515638-A | Dolichosin A and preparation method of intermediate thereof | 成都科岭源医药技术有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118515682-A | Dolichosin A preparation method and intermediate thereof | 成都科岭源医药技术有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118515638-A | Dolichosin A and preparation method of intermediate thereof | 成都科岭源医药技术有限公司 | 2024-08-20 | — | — | CN | disclosed |