Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921284 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPSR1NOTUMNPC1KMT2A | |
| SCHEMBL12615992 | 0.78 | ALDH1A1 (0.68) | ALDH1A1NPSR1NOTUMNPC1KMT2A | |
| SCHEMBL11127908 | 0.77 | MYC (0.47) | MYCNOTUM | |
| SCHEMBL8109135 | 0.73 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMNPC1KMT2A | |
| SCHEMBL15266274 | 0.71 | MAPK1 (0.49) | ALDH1A1MYCNOTUMNPC1KMT2A | |
| SCHEMBL4925703 | 0.71 | NPC1 (0.58) | ALDH1A1NPSR1MYCNOTUMNPC1 | |
| SCHEMBL16144650 | 0.70 | ALDH1A1 (0.54) | ALDH1A1NPSR1NOTUMNPC1KMT2A | |
| SCHEMBL13995836 | 0.70 | NPC1 (0.68) | ALDH1A1NPSR1NOTUMNPC1KMT2A | |
| SCHEMBL3328193 | 0.70 | NPC1 (0.57) | ALDH1A1NPSR1NOTUMNPC1KMT2A | |
| SCHEMBL5549180 | 0.69 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418526-A | Compound with mono-sulfophenyl tetrazole structure and application of compound with mono-sulfophenyl tetrazole structure | HANGZHOU JIAMA BIOLOGICAL TECH CO LTD | 2016-03-23 | — | — | CN | disclosed |