Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20237265 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL28955008 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL5549180 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL14242848 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL5330184 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL30084182 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL8540440 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL8109135 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL436604 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL7768909 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071328-A1 | Propynoic Acid Carbamoyl Methyl-Amides and Pharmaceutical Compositions and Methods Based Thereon | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2012129452-A2 | PROPYNOIC ACID CARBAMOYL METHYL-ALMIDES AND PHARMACEUTICAL COMPOSITIONS AND METHODS BASED THEREON | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071328-A1 | Propynoic Acid Carbamoyl Methyl-Amides and Pharmaceutical Compositions and Methods Based Thereon | RELA, NFE2, NCOA1 | ALDH1A1 1558/4885NPSR1 3244/4885NOTUM 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.