Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812215 | 0.90 | ALDH1A1 (0.65) | MYCALDH1A1HDAC6HDAC8MAPK1 | |
| SCHEMBL1026202 | 0.87 | NOTUM (0.61) | MYCALDH1A1HDAC6ESR1ESR2 | |
| SCHEMBL1075113 | 0.86 | ALDH1A1 (0.53) | MYCALDH1A1HDAC6HDAC8MAPK1 | |
| SCHEMBL30810841 | 0.83 | HDAC6 (0.51) | MYCHDAC6ESR1ESR2HDAC8 | |
| SCHEMBL2277266 | 0.83 | HDAC6 (0.51) | MYCHDAC6ESR1ESR2HDAC8 | |
| SCHEMBL25253125 | 0.83 | MYC (0.46) | MYCALDH1A1HDAC6ESR1ESR2 | |
| SCHEMBL14101079 | 0.83 | ESR1 (0.70) | MYCALDH1A1HDAC6ESR1ESR2 | |
| SCHEMBL6645620 | 0.82 | MYC (0.45) | MYCHDAC6ESR1ESR2HDAC8 | |
| SCHEMBL6645616 | 0.82 | MYC (0.45) | MYCHDAC6ESR1ESR2HDAC8 | |
| SCHEMBL1648634 | 0.81 | ESR2 (0.68) | ESR1ESR2NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431422-A | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2016-03-23 | — | — | CN | disclosed |