SCHEMBL28052801

SCHEMBL28052801

COC(=O)c1ccc(SS)c(Sc2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.52
L3MBTL1 Q9Y468 6/20 0.52
ALDH1A1 P00352 5/20 0.52
HPGD P15428 5/20 0.52
KDM4E B2RXH2 4/20 0.52
LMNA P02545 3/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 2/20 0.51
MEN1 O00255 1/20 0.51
TP53 P04637 1/20 0.51
ALOX12 P18054 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TSHR P16473 1/20 0.46
RAB9A P51151 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
CASP3 P42574 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6516445 0.88 MAPT (0.55) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL6512344 0.84 MAPT (0.53) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL6521928 0.83 MAPT (0.51) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL6521932 0.83 ALDH1A1 (0.51) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL6516137 0.83 MAPT (0.51) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL11665329 0.82 ALDH1A1 (0.55) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL18123682 0.82 KDM4E (0.54) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL10651357 0.82 HPGD (0.58) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL10651004 0.82 L3MBTL1 (0.58) MAPTL3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL25465981 0.81 ALDH1A1 (0.59) MAPTL3MBTL1ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105381573-B Golf 邓禄普体育用品株式会社 2018-03-09 CN disclosed
CN-103446720-B Golf ball 邓禄普体育用品株式会社 2017-05-10 CN disclosed
CN-105381573-A GOLF BALL DUNLOP SPORTS CO LTD 2016-03-09 CN disclosed
CN-103446721-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446722-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed