Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 2/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17122422 | 0.92 | MAPT (0.74) | DDX3XPTGS1MAPTMEN1HTT | |
| SCHEMBL30969167 | 0.88 | PTGS1 (0.74) | DDX3XPTGS1MAPTMEN1HTT | |
| SCHEMBL17664317 | 0.84 | KMT2A (0.81) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL30314470 | 0.83 | DDX3X (1.00) | DDX3XPTGS1MAPTMEN1HTT | |
| SCHEMBL1657499 | 0.83 | DDX3X (1.00) | DDX3XPTGS1MAPTMEN1HTT | |
| SCHEMBL671986 | 0.82 | MAPT (0.78) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL30101230 | 0.82 | KMT2A (0.90) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL5597699 | 0.82 | KMT2A (0.90) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL11003476 | 0.82 | MAPT (0.68) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL16246935 | 0.82 | KMT2A (0.77) | PTGS1MAPTMEN1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103354809-A | Arylurea compound, intermediate and use thereof | SHANGHAI INST PHARM INDUSTRY | 2013-10-16 | — | — | CN | claimed |
| CN-103354809-B | A kind of aryl urea compounds, its intermediate and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-01-13 | — | — | CN | disclosed |