Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.74 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
| ▸ | DDX3X | O00571 | 1/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17122422 | 0.89 | MAPT (0.74) | PTGS1DDX3XEPHX2MAPTMEN1 | |
| SCHEMBL28052817 | 0.88 | DDX3X (0.70) | PTGS1BAZ1AMTORDDX3XMAPT | |
| SCHEMBL29572527 | 0.85 | KMT2A (0.77) | PTGS1BAZ1AMTORMAPTMEN1 | |
| SCHEMBL16246935 | 0.85 | KMT2A (0.77) | PTGS1BAZ1AMTORMAPTMEN1 | |
| SCHEMBL12973545 | 0.84 | EPHX2 (0.81) | PTGS1BAZ1AMTOREPHX2MAPT | |
| SCHEMBL30314470 | 0.83 | DDX3X (1.00) | PTGS1DDX3XEPHX2MAPTMEN1 | |
| SCHEMBL1657499 | 0.83 | DDX3X (1.00) | PTGS1DDX3XEPHX2MAPTMEN1 | |
| SCHEMBL3946302 | 0.83 | BAZ1A (1.00) | BAZ1AMTOREPHX2MAPTMEN1 | |
| SCHEMBL255088 | 0.83 | MTOR (1.00) | BAZ1AMTOREPHX2MAPTMEN1 | |
| SCHEMBL4548071 | 0.82 | EPHX2 (0.85) | BAZ1AMTOREPHX2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206490-B | Indazole-3-carboxylic acid derivative with antitumor activity, preparation method and application | 国王医学科技(山东)有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118206490-A | Indazole-3-carboxylic acid derivative with antitumor activity, preparation method and application | 国王医学科技(山东)有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118206490-B | Indazole-3-carboxylic acid derivative with antitumor activity, preparation method and application | 国王医学科技(山东)有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118206490-A | Indazole-3-carboxylic acid derivative with antitumor activity, preparation method and application | 国王医学科技(山东)有限公司 | 2024-06-18 | — | — | CN | disclosed |