Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120662 | 0.84 | NPC1 (0.39) | NPC1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL29070667 | 0.83 | NPC1 (0.49) | NPC1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL5939 | 0.81 | NPC1 (0.55) | NPC1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL23120224 | 0.80 | MAPT (0.39) | RAB9AMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL29949311 | 0.80 | MAPT (0.39) | RAB9AMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL27987448 | 0.79 | NPC1 (0.41) | NPC1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL27858444 | 0.75 | L3MBTL1 (0.49) | GAAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL31349356 | 0.75 | MAP4K4 (0.45) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL10385942 | 0.75 | NPC1 (0.47) | NPC1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL280520 | 0.74 | TNKS (0.54) | NPC1RAB9AGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104194778-B | Phosphorus-oxygen groups modifies the preparation method of N-Phenyl-benzoimidazol electron transport material, synthetic method and electro phosphorescent device | HEILONGJIANG UNIVERSITY (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-104194778-B | Phosphorus-oxygen groups modifies the preparation method of N-Phenyl-benzoimidazol electron transport material, synthetic method and electro phosphorescent device | HEILONGJIANG UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-104194778-B | Phosphorus-oxygen groups modifies the preparation method of N-Phenyl-benzoimidazol electron transport material, synthetic method and electro phosphorescent device | HEILONGJIANG UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |