Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TNKS | O95271 | 2/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286054 | 0.81 | HDAC6 (0.60) | TNKSTNKS2PARP1CYP1A1CYP1B1 | |
| SCHEMBL28052830 | 0.81 | NPC1 (0.49) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL27761849 | 0.80 | NPC1 (0.56) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL28136411 | 0.79 | TNKS (0.56) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL7146757 | 0.79 | NPC1 (0.55) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL6368201 | 0.79 | NPC1 (0.55) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL56854 | 0.79 | RAB9A (0.55) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL1895948 | 0.79 | NPC1 (0.55) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL18300831 | 0.79 | NPC1 (0.55) | NPC1RAB9AGAATNKSTNKS2 | |
| SCHEMBL27961299 | 0.79 | NPC1 (0.55) | NPC1RAB9AGAATNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659846-A | N-substituted phenylbenzimidazole trivalent-iridium organometallic complex and its preparation method and use | NINGBO INST MAT TECH & ENG CAS | 2012-09-12 | — | — | CN | claimed |
| CN-113004336-B | Transition metal complexes, polymers, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115385909-B | Method for synthesizing imidazophenanthridine compounds through palladium-copper co-catalysis | 江苏师范大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-115385909-B | Method for synthesizing imidazophenanthridine compounds through palladium-copper co-catalysis | 江苏师范大学 | 2023-09-29 | — | — | CN | disclosed |
| US-11696492-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| CN-114889271-B | Hot-rolled non-woven fabric and preparation method thereof | 河南省超亚医药器械有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-115385909-A | Method for synthesizing imidazophenanthridine compound under co-catalysis of palladium and copper | 江苏师范大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-115385909-A | Method for synthesizing imidazophenanthridine compound under co-catalysis of palladium and copper | 江苏师范大学 | 2022-11-25 | — | — | CN | disclosed |
| US-11424420-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-08-23 | — | — | US | disclosed |
| CN-114889271-A | Hot-rolled non-woven fabric and preparation method thereof | 河南省超亚医药器械有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-111747988-A | Organic electroluminescent material and device | 环球展览公司 | 2020-10-09 | — | — | CN | disclosed |
| US-20200220090-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-07-09 | — | — | US | disclosed |
| CN-109651443-A | Electroluminescent organic material and device | 环球展览公司 | 2019-04-19 | — | — | CN | disclosed |
| US-20190074455-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-03-07 | — | — | US | disclosed |
| CN-109180590-A | A method of Benzoheterocyclic compounds are quickly prepared using physical grinding method under room temperature solvent-free | 福建医科大学 | 2019-01-11 | — | — | CN | disclosed |
| WO-2015093813-A2 | ORGANIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 두산 | 2015-06-25 | — | — | WO | disclosed |
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-08-16 | — | — | US | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110046105-A1 | Heterocycle-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising them and use thereof | SANOFI-AVENTIS (FR) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | NPC1 1247/4885RAB9A 4369/4885GAA 552/4885 |
| US-20110046105-A1 | Heterocycle-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising them and use thereof | GIPR, DDC, PGC | NPC1 2432/4885RAB9A 1182/4885GAA 160/4885 |
| US-20200220090-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, ODC1 | NPC1 1914/4885RAB9A 3437/4885GAA 1427/4885 |
| US-20190074455-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | L1CAM, SOD1, OR10J3 | NPC1 3617/4885RAB9A 2153/4885GAA 535/4885 |
| US-11696492-B2 | Organic electroluminescent materials and devices | OCIAD1, OCIAD2, ODC1 | NPC1 1914/4885RAB9A 3437/4885GAA 1427/4885 |
| US-11424420-B2 | Organic electroluminescent materials and devices | L1CAM, SOD1, OR10J3 | NPC1 3617/4885RAB9A 2153/4885GAA 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.