Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25794823 | 0.87 | TDP1 (0.62) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL187037 | 0.86 | FFAR4 (0.59) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL25344842 | 0.84 | FFAR4 (0.57) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL20509598 | 0.84 | FFAR4 (0.64) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL25247535 | 0.83 | FFAR4 (0.56) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL1146881 | 0.83 | FFAR4 (0.55) | FFAR4SLC6A3KMT2ASLC6A4MEN1 | |
| SCHEMBL2545851 | 0.82 | FFAR4 (0.55) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL1722284 | 0.82 | FFAR4 (0.55) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL5763096 | 0.82 | FFAR4 (0.55) | FFAR4TDP1SLC6A3KMT2ASLC6A4 | |
| SCHEMBL28826108 | 0.81 | KEAP1 (0.46) | FFAR4KMT2AHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348089-A | Preparation method of roflumilast midbody | WEIHAI DISU PHARMACEUTICAL CO LTD | 2016-02-24 | — | — | CN | disclosed |