Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16616127 | 0.88 | TDP1 (0.57) | TDP1FFAR4KMT2AMEN1KDM4E | |
| SCHEMBL1546433 | 0.87 | TSHR (0.54) | TDP1FFAR4KMT2AMEN1KDM4E | |
| SCHEMBL28052851 | 0.87 | FFAR4 (0.60) | TDP1FFAR4KMT2AMEN1KDM4E | |
| SCHEMBL187037 | 0.86 | FFAR4 (0.59) | TDP1FFAR4KMT2AMEN1KDM4E | |
| SCHEMBL17535871 | 0.85 | TDP1 (0.51) | TDP1FFAR4KMT2AMEN1KDM4E | |
| SCHEMBL25344842 | 0.84 | FFAR4 (0.57) | TDP1FFAR4KMT2AMEN1KDM4E | |
| SCHEMBL20509598 | 0.84 | FFAR4 (0.64) | TDP1FFAR4KMT2AMEN1SLC6A4 | |
| SCHEMBL15048810 | 0.83 | TSHR (0.51) | TDP1FFAR4KMT2AMEN1KDM4E | |
| SCHEMBL30628273 | 0.83 | CYP3A4 (0.61) | TDP1FFAR4KMT2AKDM4EALDH1A1 | |
| SCHEMBL4271221 | 0.83 | CYP3A4 (0.61) | TDP1FFAR4KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130050-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS AND USE THEREOF FOR THE TREATMENT AND MANAGEMENT OF PAIN | PSY THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |