Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743625 | 0.88 | PTGS1 (0.42) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL11743616 | 0.88 | PTGS1 (0.42) | MAPTRAB9ACASP3SENP8SENP7 | |
| Potassium Ion SCHEMBL11744394 | 0.83 | PTGS1 (0.42) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL11744400 | 0.83 | PHLPP2 (0.49) | MAPTRAB9ACASP3SENP8SENP7 | |
| Potassium Ion SCHEMBL11744384 | 0.83 | PTGS1 (0.42) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL11743145 | 0.78 | MEN1 (0.62) | MAPTKDM4EHPGDALDH1A1TSHR | |
| SCHEMBL11743138 | 0.78 | MEN1 (0.62) | MAPTKDM4EHPGDALDH1A1TSHR | |
| SCHEMBL10334138 | 0.77 | CA1 (0.58) | RAB9AL3MBTL1KDM4EHSD17B10PTGS1 | |
| SCHEMBL10334139 | 0.77 | CA1 (0.58) | RAB9AL3MBTL1KDM4EHSD17B10PTGS1 | |
| Dimethyl Phthalate SCHEMBL28528385 | 0.72 | MAPT (0.70) | MAPTRAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367489-A | Method for synthesizing salazosulfapyridine using pyridazol as raw material | SUZHOU TONGHUA PHARMACEUTICAL CO LTD | 2016-03-02 | — | — | CN | disclosed |
| CN-105348184-A | Preparation method for sulfasalazine | SUZHOU TONGHUA MEDICINE CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-105330599-A | Method for synthesizing salazosulfapyridine by utilizing 2-aminopyridine as raw material | SUZHOU TONGHUA PHARMACEUTICAL CO LTD | 2016-02-17 | — | — | CN | disclosed |