Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10334139 | 1.00 | CA1 (0.58) | CA1CA2PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL10334271 | 0.87 | EGFR (0.48) | CA1CA2PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL10334272 | 0.87 | EGFR (0.48) | CA1CA2PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL10334090 | 0.82 | PTGS2 (0.71) | CA1CA2PTGS2PTGS1RAB9A | |
| SCHEMBL10334089 | 0.82 | PTGS2 (0.71) | CA1CA2PTGS2PTGS1RAB9A | |
| SCHEMBL28052984 | 0.77 | MAPT (0.49) | CA1CA2PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL10695116 | 0.74 | CA2 (0.59) | CA1CA2PTGS2SMN1; SMN2RAB9A | |
| SCHEMBL10354505 | 0.74 | CA2 (1.00) | CA1CA2PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL20219231 | 0.74 | CA2 (1.00) | CA1CA2PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL10695121 | 0.74 | CA2 (0.59) | CA1CA2PTGS2SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933330-A | PSORIASIS | DAK-LABORATORIET (DK) | 1990-06-12 | — | — | US | disclosed |
| EP-0291159-A2 | Aminosalicylic-acid derivatives for the treatment of psoriasis | DAK-LABORATORIET A/S (DK) | 1988-11-17 | — | — | EP | disclosed |