SCHEMBL28053010

SCHEMBL28053010

Nc1ccc(-c2ccc(N)cc2-c2cccc(-c3ccccc3)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
HSD17B10 Q99714 3/20 0.56
TAAR1 Q96RJ0 2/20 0.56
MAOA P21397 1/20 0.55
ALDH1A1 P00352 7/20 0.44
HPGD P15428 5/20 0.44
MAPT P10636 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
KDM4E B2RXH2 3/20 0.44
LMNA P02545 3/20 0.44
GLA P06280 2/20 0.44
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
ALOX15 P16050 2/20 0.42
TP53 P04637 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24079307 0.98 MAOA (0.57) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL16820316 0.96 MAOA (0.59) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL24079330 0.96 MAOA (0.59) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL29458681 0.92 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL5459730 0.92 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL30670342 0.92 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL24945475 0.90 HSD17B10 (0.62) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL25301803 0.90 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL650894 0.90 CYP3A4 (0.61) CYP3A4TDP1HSD17B10TAAR1MAOA
SCHEMBL21582646 0.90 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105339416-A Polyimide, resin film, and metal-clad laminate NIPPON STEEL & SUMIKIN CHEM CO 2016-02-17 CN disclosed
CN-103649174-B Crosslinked polyimide resin, its manufacture method, adhesive resin composition and application thereof NIPPON STEEL & SUMIKIN CHEMICAL CO.,LTD. (JP) 2016-02-03 CN disclosed