SCHEMBL28053107

SCHEMBL28053107

CC(C)CS(=O)(=O)NS(C)(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36
GRIA1 P42261 3/20 0.36
MAPT P10636 1/20 0.33
CXCR1 P25024 2/20 0.31
CXCR2 P25025 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3146291 0.86 GRIA1 (0.40) GRIA1MAPT
SCHEMBL605797 0.72
SCHEMBL668824 0.72 GRIA1 (0.34) GRIA1MAPT
SCHEMBL21867036 0.72 MEN1 (0.34)
SCHEMBL241512 0.71 CA2 (0.37) CA2
SCHEMBL605796 0.70
SCHEMBL20440093 0.70
SCHEMBL8277105 0.70 GRIA1 (0.37) GRIA1MAPT
SCHEMBL5438408 0.70
SCHEMBL13155208 0.70 ALDH1A1 (0.35) GRIA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105473542-A Method for manufacturing optically active 5-hydroxy-3-ketoesters NISSAN CHEMICAL IND LTD 2016-04-06 CN disclosed