Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15703 | 0.87 | TDP1 (1.00) | TSHRTDP1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL4381222 | 0.85 | TDP1 (0.95) | TSHRTDP1CA12CA1CA2 | |
| Bromide SCHEMBL28053215 | 0.85 | TDP1 (0.95) | TSHRTDP1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL2864286 | 0.85 | TDP1 (0.95) | TSHRTDP1CA12CA1CA2 | |
| SCHEMBL11118343 | 0.85 | TSHR (0.70) | TSHRTDP1CA12CA1CA2 | |
| Phosphoric Acid SCHEMBL28053197 | 0.84 | TDP1 (0.76) | TSHRTDP1CA12CA1CA2 | |
| Acetic Acid SCHEMBL28053212 | 0.84 | TDP1 (0.76) | TSHRTDP1CA12CA1CA2 | |
| Sulfuric Acid SCHEMBL8644382 | 0.83 | TDP1 (0.52) | TSHRTDP1CA12CA1CA2 | |
| Sulfuric Acid SCHEMBL11373042 | 0.82 | TSHR (0.48) | TSHRTDP1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL3790560 | 0.81 | TDP1 (0.86) | TSHRTDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237431-B | A kind of preparation of phenaetin and method for crystallising | 山东国润生物医药有限公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-105237431-A | Preparation and crystallization method of phenacetin | SHANDONG GREEN BIO PHARMACEUTICAL CO LTD | 2016-01-13 | — | — | CN | disclosed |