Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15703 | 0.87 | TDP1 (1.00) | TDP1TSHRNPC1RAB9ATP53 | |
| Bromide SCHEMBL28053215 | 0.85 | TDP1 (0.95) | TDP1TSHRNPC1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL4381222 | 0.85 | TDP1 (0.95) | TDP1TSHRNPC1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL2864286 | 0.85 | TDP1 (0.95) | TDP1TSHRNPC1RAB9ATP53 | |
| Acetic Acid SCHEMBL28053212 | 0.84 | TDP1 (0.76) | TDP1TSHRNPC1RAB9ATP53 | |
| Sulfuric Acid SCHEMBL28053148 | 0.84 | TSHR (0.76) | TDP1TSHRNPC1RAB9ATP53 | |
| SCHEMBL11088120 | 0.81 | TDP1 (0.86) | TDP1TSHRNPC1RAB9ATP53 | |
| SCHEMBL3790560 | 0.81 | TDP1 (0.86) | TDP1TSHRNPC1RAB9ATP53 | |
| Dimethylamine SCHEMBL656266 | 0.81 | TDP1 (0.86) | TDP1TSHRNPC1RAB9ATP53 | |
| SCHEMBL6655854 | 0.81 | TSHR (0.70) | TDP1TSHRNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237431-B | A kind of preparation of phenaetin and method for crystallising | 山东国润生物医药有限公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-105237431-A | Preparation and crystallization method of phenacetin | SHANDONG GREEN BIO PHARMACEUTICAL CO LTD | 2016-01-13 | — | — | CN | disclosed |