Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.43 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235104 | 0.81 | CCR4 (0.51) | CCR4TDP1MEN1KMT2AKDM4E | |
| SCHEMBL28163871 | 0.79 | CCR4 (0.54) | CCR4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16235832 | 0.79 | CCR4 (0.61) | CCR4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28053283 | 0.77 | S100A9 (0.42) | CCR4TDP1ALDH1A1F2GLA | |
| SCHEMBL16235106 | 0.76 | CCR4 (0.51) | CCR4TDP1MEN1KMT2AKDM4E | |
| SCHEMBL11724326 | 0.70 | KMT2A (0.47) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29023897 | 0.70 | ALDH1A1 (0.50) | CCR4TDP1MEN1KMT2AKDM4E | |
| SCHEMBL29967856 | 0.70 | ALDH1A1 (0.50) | CCR4TDP1MEN1KMT2AKDM4E | |
| SCHEMBL23567060 | 0.69 | LMNA (0.73) | CCR4TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL16235556 | 0.69 | KMT2A (0.51) | CCR4MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |