Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600177 | 0.72 | NPY5R (0.49) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14610321 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1SRD5A2LMNAMGAM | |
| Hydrochloric Acid SCHEMBL9544492 | 0.72 | BCHE (0.42) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29365290 | 0.72 | KDM4E (0.50) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6766148 | 0.71 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAMGAMHPGD | |
| SCHEMBL9544495 | 0.70 | DRD4 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2837730 | 0.68 | KDM4E (0.54) | KDM4EALDH1A1CYP3A4GAAPOLB | |
| SCHEMBL8172786 | 0.68 | KDM4E (1.00) | KDM4EALDH1A1GSRPOLBHPGD | |
| SCHEMBL319496 | 0.68 | MGAM (0.44) | KDM4EMGAMALOX15TSHRACMSD | |
| SCHEMBL11794463 | 0.68 | ALDH1A1 (0.52) | KDM4EALDH1A1CYP1A2CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294678-A | 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H, 5H-benzo-quinoline-2-carboxylic acid preparation method | NANJING GRITPHARMA CO LTD | 2016-02-03 | — | — | CN | disclosed |
| CN-105294678-A | 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H, 5H-benzo-quinoline-2-carboxylic acid preparation method | NANJING GRITPHARMA CO LTD | 2016-02-03 | — | — | CN | disclosed |