SCHEMBL9544495

SCHEMBL9544495

COC(=N)c1ccc2c(n1)-c1ccccc1CCC2

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.41
NPY5R Q15761 4/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TACR3 P29371 1/20 0.38
BCHE P06276 1/20 0.37
POLB P06746 2/20 0.36
IKBKB O14920 1/20 0.36
CYP2A6 P11509 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
HRH4 Q9H3N8 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9544492 0.80 BCHE (0.42) DRD4NPY5RKDM4EALDH1A1BCHE
SCHEMBL28053317 0.70 KDM4E (0.51) KDM4EALDH1A1POLBCYP1A2CYP3A4
SCHEMBL9541655 0.69 CCR1 (0.47) DRD4NPY5RKDM4EALDH1A1BCHE
SCHEMBL9544488 0.66 DRD4 (0.43) DRD4NPY5RKDM4EALDH1A1BCHE
SCHEMBL14114235 0.66 MEN1 (0.42) KDM4EALDH1A1POLBNPC1RAB9A
SCHEMBL9369148 0.65 DRD4 (0.43) DRD4NPY5RKDM4EALDH1A1BCHE
SCHEMBL9369565 0.65 DRD4 (0.42) DRD4NPY5RKDM4EALDH1A1BCHE
SCHEMBL15759146 0.64 KDM4E (0.57) DRD4NPY5RKDM4EALDH1A1BCHE
SCHEMBL1509445 0.64 KDM4E (0.57) DRD4NPY5RKDM4EALDH1A1BCHE
SCHEMBL9368974 0.64 NPY5R (0.60) DRD4NPY5RKDM4EALDH1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993014080-A1 BRIDGED HETEROCYCLIC FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-22 WO disclosed