Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19815870 | 0.86 | PARP1 (0.62) | PARP1SMN1; SMN2RAB9ANPC1SRC | |
| SCHEMBL28128312 | 0.83 | PARP1 (0.59) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL28223910 | 0.82 | SIRT5 (0.59) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL19826614 | 0.79 | PARP1 (0.61) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL7567751 | 0.75 | ADORA3 (0.49) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL9261629 | 0.74 | PARP1 (0.64) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL29563063 | 0.74 | PARP1 (1.00) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL182864 | 0.74 | PARP1 (1.00) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL4032577 | 0.74 | PARP1 (0.64) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 | |
| SCHEMBL29967369 | 0.74 | PARP1 (1.00) | PARP1SMN1; SMN2RAB9ANPC1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889963-B | The similar thing of quinazolinone and the similar thing of quinazolinone are being used for the treatment of or are preventing the application in some virus infection | SOUTHERN RESEARCH INSTITUTE (US) | 2016-01-20 | — | — | CN | disclosed |