Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441561 | 0.78 | METAP1 (0.69) | METAP1METAP2ALDH1A1KDM4EHPGD | |
| SCHEMBL18042290 | 0.78 | KDM4E (0.52) | METAP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6382797 | 0.77 | METAP1 (0.68) | METAP1METAP2ALDH1A1KDM4EHPGD | |
| SCHEMBL9990569 | 0.77 | METAP1 (0.63) | METAP1METAP2RAB9ANPY5RPDE10A | |
| SCHEMBL1811572 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL680854 | 0.74 | METAP2 (0.65) | METAP1METAP2ALDH1A1NPC1RAB9A | |
| SCHEMBL16332241 | 0.74 | ALDH1A1 (0.67) | METAP1METAP2ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL4456676 | 0.73 | METAP2 (0.63) | METAP1METAP2ALDH1A1NPC1RAB9A | |
| SCHEMBL4875487 | 0.72 | METAP1 (0.67) | METAP1METAP2NPY5R | |
| SCHEMBL369485 | 0.72 | METAP2 (0.61) | METAP1METAP2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105246918-A | Growth hormone secretagogue receptor related protein, nucleic acid, preparation method and application thereof | WANG QINGHUA | 2016-01-13 | — | — | CN | disclosed |