Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597729 | 0.84 | MAPT (0.65) | SIGMAR1MAPTGBA1 | |
| SCHEMBL3597725 | 0.84 | MAPT (0.65) | SIGMAR1MAPTGBA1 | |
| SCHEMBL3601179 | 0.84 | MAPT (0.65) | SIGMAR1MAPTGBA1 | |
| SCHEMBL17048017 | 0.84 | MAPT (0.65) | SIGMAR1MAPTGBA1 | |
| SCHEMBL2271581 | 0.84 | MAPT (0.65) | SIGMAR1MAPTGBA1 | |
| SCHEMBL3601182 | 0.84 | MAPT (0.65) | SIGMAR1MAPTGBA1 | |
| SCHEMBL4513431 | 0.76 | GBA1 (0.52) | SIGMAR1MAPTGBA1ACHEHRH3 | |
| SCHEMBL18857789 | 0.76 | SIGMAR1 (0.54) | SIGMAR1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL22668719 | 0.76 | GBA1 (0.52) | SIGMAR1MAPTGBA1ACHEHRH3 | |
| SCHEMBL14660575 | 0.76 | GBA1 (0.52) | SIGMAR1MAPTGBA1ACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105246888-A | Imidazopyridine compounds and uses thereof | TECHNOLOGY SG L P | 2016-01-13 | — | — | CN | disclosed |