SCHEMBL28053604

SCHEMBL28053604

C=C(C)C(=O)OC(OC(C)C)([SiH2]OCC)C(C)OC(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19068051 0.68 TSHR (0.38) TSHR
SCHEMBL16153156 0.68 TSHR (0.38) TSHR
SCHEMBL5493247 0.65 TSHR (0.34) TSHRTHRB
SCHEMBL25475950 0.64 TSHR (0.41) TSHRTHRB
SCHEMBL16153153 0.63 TSHR (0.38) TSHRTHRB
SCHEMBL10941495 0.63 ALDH1A1 (0.36) TSHR
SCHEMBL2696372 0.62 TSHR (0.37) TSHRTHRB
SCHEMBL10455143 0.62 TSHR (0.37) TSHRTHRB
SCHEMBL18233423 0.62 TSHR (0.47) TSHRTHRB
SCHEMBL11701361 0.61 THRB (0.40) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377270-A Proton-binding polymers for oral administration TRICIDA INC 2016-03-02 CN disclosed