SCHEMBL28053710

SCHEMBL28053710

CCCC(c1ccccc1)C(c1ccccc1)C(C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 2/20 0.43
MME P08473 2/20 0.43
AOC3 Q16853 1/20 0.40
CYP2D6 P10635 2/20 0.39
SRC P12931 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39
POLB P06746 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 2/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28053724 0.86 HKDC1 (0.47) PDPK1MMECYP2D6SRCPOLB
SCHEMBL28053720 0.82 CYP3A4 (0.39) PDPK1MMECYP3A4CYP2C19PPARG
SCHEMBL13082206 0.79 MME (0.44) MMEAOC3CYP2D6SRCCYP3A4
SCHEMBL30038865 0.79 MME (0.44) MMEAOC3CYP2D6SRCCYP3A4
SCHEMBL2353775 0.78 TAAR1 (0.48) MMEAOC3CYP2D6CYP1A2CYP3A4
SCHEMBL5320862 0.77 CYP2D6 (0.46) AOC3CYP2D6SRCCYP2C9CYP2C19
SCHEMBL8157573 0.77 AOC3 (0.48) AOC3SLC6A2SLC6A3LMNA
SCHEMBL1452589 0.77 SRC (0.56) PDPK1CYP2D6SRCCYP1A2CYP2C19
SCHEMBL10441680 0.76 PDPK1 (0.53) PDPK1CYP2D6SRCCYP1A2CYP3A4
Benzoic Acid SCHEMBL1782197 0.75 DAO (0.47) AOC3SLC6A2SLC6A3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN claimed
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN disclosed