Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5289685 | 0.90 | POLB (0.48) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL6533633 | 0.88 | CSNK1E (0.44) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL497439 | 0.85 | CYP2D6 (0.49) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL1162118 | 0.85 | CYP2D6 (0.49) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL22338831 | 0.85 | CYP2D6 (0.49) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL5320088 | 0.84 | TAS1R3 (0.43) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL7653146 | 0.84 | HRH1 (0.50) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL839858 | 0.84 | CYP2D6 (0.47) | CYP2D6MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL5322662 | 0.83 | PPARG (0.52) | CYP2D6SLC1A2SLC1A3SLC1A1 | |
| SCHEMBL5565838 | 0.82 | CYP2D6 (0.46) | CYP2D6MEN1CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | CYP2D6 3900/4885MEN1 927/4885CYP2C9 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.