Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891559 | 0.88 | KAT6A (0.41) | MAPTHPGDLMNACYP1B1RECQL | |
| SCHEMBL27840804 | 0.88 | MAPT (0.35) | MAPTALDH1A1CYP3A4HPGDLMNA | |
| SCHEMBL5324147 | 0.87 | MAPT (0.38) | MAPTALDH1A1CYP3A4HPGDLMNA | |
| SCHEMBL27869381 | 0.87 | ALDH1A1 (0.43) | MAPTALDH1A1CYP3A4HPGDLMNA | |
| SCHEMBL27821481 | 0.84 | MAOB (0.46) | MAPTALDH1A1HPGDALKBH2ALKBH3 | |
| SCHEMBL27840781 | 0.83 | KMT2A (0.42) | MAPTALDH1A1CYP3A4LMNACYP1B1 | |
| SCHEMBL27821480 | 0.82 | KMT2A (0.42) | MAPTCYP3A4LMNACYP1B1RECQL | |
| SCHEMBL27840910 | 0.80 | POLB (0.38) | LMNACYP1B1BCHEMAOBHDAC3 | |
| SCHEMBL3772640 | 0.80 | MAOB (0.48) | MAPTALDH1A1CYP1B1BCHEMAOB | |
| SCHEMBL27840729 | 0.77 | MAPT (0.47) | MAPTALDH1A1LMNACYP1B1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377895-A | Antibodies against TM4SF5 and anticancer compositions comprising the same | UNIV HALLYM IND ACAD COOP FOUND | 2016-03-02 | — | — | CN | disclosed |