SCHEMBL28053750

SCHEMBL28053750

O=C(O)CCCCC(=O)OC(=O)c1ccc(C(=O)OC2(O)CCCCC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.33
PPARA Q07869 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
PDE4B Q07343 1/20 0.32
POLB P06746 2/20 0.32
HSD17B10 Q99714 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28189323 0.87 KMT2A (0.33) SLC6A2SLC6A4SLC6A3PRSS1CTSG
SCHEMBL1134580 0.81 MAPK1 (0.46) MAPK1SMN1; SMN2PPARAHDAC3HDAC4
SCHEMBL28061190 0.81
SCHEMBL27524321 0.80 MAPK1 (0.49) MAPK1PPARAHDAC3HDAC4HDAC1
SCHEMBL26127917 0.80 MAPK1 (0.49) MAPK1PPARAHDAC3HDAC4HDAC1
SCHEMBL8379024 0.80 MAPK1 (0.49) MAPK1PPARAHDAC3HDAC4HDAC1
SCHEMBL29154817 0.80 MAPK1 (0.49) MAPK1PPARAHDAC3HDAC4HDAC1
SCHEMBL27623312 0.80 RAB9A (0.36) SLC6A2SLC6A4SLC6A3NPC1LMNA
SCHEMBL11149812 0.78 LMNA (0.41) MAPK1SMN1; SMN2PPARAHDAC11HSD17B10
SCHEMBL8815355 0.78 PDE4B (0.47) MAPK1SMN1; SMN2PPARAHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105367770-B A kind of aliphatic-aromatic-polylactic-acid block copolymer 中国科学院长春应用化学研究所 2018-06-29 CN disclosed
CN-105367770-A Aliphatic-aromatic-polylactic acid block copolymer CHANGCHUN INST APPLIED CHEMISTRY CAS 2016-03-02 CN disclosed