Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | SORD | Q00796 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396825 | 0.87 | NQO1 (0.67) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL20848068 | 0.83 | CA12 (0.70) | CA12CA9ALDH1A1LMNAMAOA | |
| SCHEMBL1535058 | 0.80 | NQO1 (0.62) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL30228412 | 0.79 | KCNA3 (0.62) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL28227416 | 0.79 | CA12 (0.70) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL5398907 | 0.79 | NQO1 (0.53) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL5691199 | 0.79 | KCNA3 (0.62) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL28143420 | 0.79 | CA12 (0.66) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL20420782 | 0.77 | NQO1 (0.50) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL31264770 | 0.77 | CA9 (0.68) | NQO1CA12CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384715-B | A kind of bromo- 4- phenyl coumarin series compound preparation method of 3- of 7- substitution | 嘉兴学院 | 2019-01-18 | — | — | CN | claimed |
| CN-108299363-B | A kind of synthetic method of 3- benzene sulfonyl class coumarin kind compound | 青岛农业大学 | 2019-10-08 | — | — | CN | disclosed |
| CN-105384715-B | A kind of bromo- 4- phenyl coumarin series compound preparation method of 3- of 7- substitution | 嘉兴学院 | 2019-01-18 | — | — | CN | disclosed |
| CN-105384715-B | A kind of bromo- 4- phenyl coumarin series compound preparation method of 3- of 7- substitution | 嘉兴学院 | 2019-01-18 | — | — | CN | disclosed |
| CN-105384715-B | A kind of bromo- 4- phenyl coumarin series compound preparation method of 3- of 7- substitution | 嘉兴学院 | 2019-01-18 | — | — | CN | disclosed |
| CN-108299363-A | A kind of synthetic method of 3- benzene sulfonyls class coumarin kind compound | 青岛农业大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-105384715-A | Preparation method of 7-substituted 3-bromo-4-phenylcoumarin series compounds | UNIV JIAXING | 2016-03-09 | — | — | CN | disclosed |